MLPA® - MRC Holland Kits

Please note before download:

  • Mix descriptions are only free of charge for customers with maintenance contract.
  • Don't hesitate to contact us, if there are any mix descriptions missing on this website.
  • To set up a new mix descriptions for you, still available at MRC Hollands website, please provide us the name of the mix (e.g. P002-D1), the version of the mix (e.g. Vs.02) and the date of its release.

  • To set up a new mix descriptions for you, not available at MRC Hollands website any more, please provide us the corresponding document by email or fax (+49-7822-440150-20).

Download

  • log into your SEQUENCE PILOT installation
  • go to category MLPA®
  • go to operation Mixes [master file]
  • press button [Import] and select the downloaded mme-file
  • if the corresponding mix already exists in your SEQUENE_PILOT installation you will be asked "Do you want to save the mix with a new name / lot?"; please press button [Yes] and complete the fields in the following dialogue; press button [OK] to save your entries
  • if the mix doesn't exist yet just press button [OK] in the following dialogue
MIX
VERSION
DATE
REGION
APPLICATION
DOWNLOAD
MIX
P300-A2
VERSION
Vs. 11
DATE
10-12-2012
REGION
Reference probes + control fragments
APPLICATION
Synthetic 'home-made' probes
MIX
P300-B1
VERSION
Vs. 14
DATE
04-09-2015
REGION
Reference probes + control fragments
APPLICATION
Synthetic 'home-made' probes
MIX
P301-A1
VERSION
Vs. 05
DATE
01-03-2013
REGION
Chr. 6, Chr. 14, Chr. 16, Chr. 17.
APPLICATION
Medulloblastoma
MIX
P301-A2
VERSION
Vs. 06
DATE
27-09-2013
REGION
Chr. 6, Chr. 14, Chr. 16, Chr. 17.
APPLICATION
Medulloblastoma
MIX
P302-A2
VERSION
Vs. 06
DATE
27-09-2013
REGION
Chr. 2, Chr. 3, Chr. 7, Chr. 9
APPLICATION
Medulloblastoma
MIX
P303-A2
VERSION
Vs. 06
DATE
27-09-2013
REGION
Chr. 1, Chr. 4, Chr. 5, Chr. 8, Chr. 10, Chr. 20
APPLICATION
Medulloblastoma
MIX
P304-A1
VERSION
Vs. 05
DATE
18-12-2012
REGION
IRF6 1q32.2
APPLICATION
Van der Woude syndrome (VWS)
MIX
P304-B1
VERSION
Vs. 07
DATE
10-02-2016
REGION
IRF6 1q32.2
APPLICATION
Van der Woude syndrome (VWS)
MIX
P305-B2
VERSION
Vs. 10
DATE
03-04-2014
REGION
AGXT, GRHPR
APPLICATION
Primary hyperoxaluria, type 1 (PH1) & type 2 (PH2)
MIX
P305-B2
VERSION
Vs. 11
DATE
12-10-2016
REGION
AGXT, GRHPR
APPLICATION
Primary hyperoxaluria, type 1 (PH1) & type 2 (PH2)
MIX
P306-B1
VERSION
Vs. 09
DATE
09-09-2015
REGION
SPG11 or KIAA1840 15q21.1
APPLICATION
Hereditary spastic paraplegia (HSP or SPG)
MIX
P306-B2
VERSION
Vs. 10
DATE
01-12-2017
REGION
SPG11 or KIAA1840 15q21.1
APPLICATION
Hereditary spastic paraplegia (HSP or SPG)
MIX
P307-B1
VERSION
Vs. 04
DATE
24-09-2011
REGION
SEPT9 17q25.3
APPLICATION
Hereditary neuralgic amyotrophy (HNA)
MIX
P307-B2
VERSION
Vs. 07
DATE
22-04-2015
REGION
SEPT9 17q25.3
APPLICATION
Hereditary neuralgic amyotrophy (HNA)
MIX
P308-B1
VERSION
Vs. 01
DATE
28-03-2013
REGION
MET 7q31, PTEN 10q23.31, LRRK2 12q12
APPLICATION
Papillary renal carcinoma, various cancers
MIX
P308-B1
VERSION
Vs. 02
DATE
07-08-2015
REGION
MET 7q31, PTEN 10q23.31, LRRK2 12q12
APPLICATION
Papillary renal carcinoma, various cancers
MIX
P309-B1
VERSION
Vs. 05
DATE
02-12-2013
REGION
MTM1 Xq28, MTMR1 Xq28
APPLICATION
Myotubular myopathy, x-linked (XLMTM)
MIX
P309-B1
VERSION
Vs. 07
DATE
20-01-2017
REGION
MTM1 Xq28, MTMR1 Xq28
APPLICATION
Myotubular myopathy, x-linked (XLMTM)
MIX
P310-B2
VERSION
Vs. 11
DATE
20-11-2015
REGION
TCOF1
APPLICATION
Treacher Collins-Franceschetti 1
MIX
P310-B3
VERSION
Vs. 12
DATE
25-10-2017
REGION
TCOF1
APPLICATION
Treacher Collins-Franceschetti 1
DOWNLOAD
MIX
P311-A2
VERSION
Vs. 06
DATE
07-08-2015
REGION
GATA4 8p23, NKX2-5 5q35, TBX5 12q24, BMP4 14q22, CRELD1 3p25
APPLICATION
Congenital Heart Disease (CHD)
MIX
P311-B1
VERSION
Vs. 07
DATE
29-07-2016
REGION
GATA4 8p23, NKX2-5 5q35, TBX5 12q24, BMP4 14q22, CRELD1 3p25
APPLICATION
Congenital Heart Disease (CHD)
MIX
P312-B1
VERSION
Vs. 05
DATE
07-03-2012
REGION
P450 oxireductase gene (POR)
APPLICATION
Congenital adrenal hyperplasia (CAH)
MIX
P312-B2
VERSION
Vs. 07
DATE
13-08-2013
REGION
P450 oxireductase gene (POR)
APPLICATION
Congenital adrenal hyperplasia (CAH)
MIX
P313-B1
VERSION
Vs. 10
DATE
07-08-2015
REGION
CREBBP 16p13.3
APPLICATION
Rubinstein–Taybi syndrome (RSTS)
MIX
P313-B2
VERSION
Vs. 11
DATE
21-10-2016
REGION
CREBBP 16p13.3
APPLICATION
Rubinstein–Taybi syndrome (RSTS)
MIX
P315-B1
VERSION
Vs. 06
DATE
19-12-2013
REGION
EGFR 7p11
APPLICATION
Tumours, solid
MIX
P315-B1
VERSION
Vs. 08
DATE
22-06-2016
REGION
EGFR 7p11
APPLICATION
Tumours, solid
MIX
P316-B2
VERSION
Vs. 11
DATE
10-12-2015
REGION
SETX 9p34.13, APTX 9p13.3, FXN 9p13
APPLICATION
Recessive Ataxias
MIX
P316-B2
VERSION
Vs. 12
DATE
26-09-2016
REGION
SETX 9p34.13, APTX 9p13.3, FXN 9p13
APPLICATION
Recessive Ataxias
MIX
P316-B3
VERSION
Vs. B3-01
DATE
30-04-2018
REGION
SETX 9p34.13, APTX 9p13.3, FXN 9p13
APPLICATION
Recessive Ataxias
MIX
P318-A2
VERSION
Vs. 04
DATE
18-07-2014
REGION
PHOX2B, GFRA3, GFRA2, GFRA1, EDNRB, NRTN, PSPN, SOX10
APPLICATION
Hirschsprung disease
MIX
P318-B1
VERSION
Vs. 06
DATE
28-09-2017
REGION
PHOX2B, GFRA3, GFRA2, GFRA1, EDNRB, NRTN, PSPN, SOX10
APPLICATION
Hirschsprung disease
MIX
P319-A2
VERSION
Vs. 06
DATE
09-12-2015
REGION
TPO, PAX8, FOXE1, NKX2-1, TSHR
APPLICATION
Thyroid dysgenesis
MIX
P319-A2
VERSION
Vs. 07
DATE
03-03-2017
REGION
TPO, PAX8, FOXE1, NKX2-1, TSHR
APPLICATION
Thyroid dysgenesis